Tec-Control Chromatography Systems
Overview
For radiopharmaceutical quality control
Tec-Control Chromatography tests the radiochemical purity of specific Tc-99m-labeled radiopharmaceuticals. The accompanying chart shows which strips and solvents are required to perform each individual test. Some solvents must be purchased separately (see Sigma-Aldrich chart) due to hazardous material shipping restrictions.
Detailed instruction manuals are packaged with each strip container, although our Radiopharmaceutical QC Procedure Manual (151-000) explains paper chromatography in greater detail.
References:
Miniaturized Chromatographic Quality-Control Procedures for Tc-99m Radiopharmaceuticals; A. Michael Zimmer and Dan G. Pavel, Journal of Nuclear Medicine, Vol. 18/12, Dec. 1977, pg. 1230.
Technical Parameters Associated with Miniaturized Chromatography Systems; Raimund A. Taukulis, A. Michael Zimmer, Dan G. Pavel and Bhupendra A. Patel, University of Illinois Medical Center, Chicago, Illinois, Journal of Nuclear Medicine Technology, Vol. 7/1.
or radiopharmaceutical quality control
Tec-Control Chromatography tests the radiochemical purity of specific Tc-99m-labeled radiopharmaceuticals. The accompanying chart shows which strips and solvents are required to perform each individual test. Some solvents must be purchased separately (see Sigma-Aldrich chart) due to hazardous material shipping restrictions.
Detailed instruction manuals are packaged with each strip container, although our Radiopharmaceutical QC Procedure Manual (151-000) explains paper chromatography in greater detail.
References:
Miniaturized Chromatographic Quality-Control Procedures for Tc-99m Radiopharmaceuticals; A. Michael Zimmer and Dan G. Pavel, Journal of Nuclear Medicine, Vol. 18/12, Dec. 1977, pg. 1230.
Technical Parameters Associated with Miniaturized Chromatography Systems; Raimund A. Taukulis, A. Michael Zimmer, Dan G. Pavel and Bhupendra A. Patel, University of Illinois Medical Center, Chicago, Illinois, Journal of Nuclear Medicine Technology, Vol. 7/1.
Solvents
RADIOPHARMACEUTICAL |
SOLVENT(S) REQUIRED* |
STRIPS REQUIRED |
Aluminum Breakthru |
150-781 10 µg/ml |
150-782 |
Aluminum Breakthru |
150-783 5 µg/ml |
150-782 |
Bicisate (Neurolite™) |
Ethyl Acetate 99.% |
150-130 |
Diphosphonate |
Acetone (HPLC Grade), Distilled H2O |
150-001 & 150-005 |
Disofenin (Hepatolite™) |
150-160, Distilled H2O |
150-122 & 150-125 |
DMSA |
Acetone (HPLC Grade), |
150-025 |
DTPA |
Acetone (HPLC Grade), Distilled H2O |
150-001 & 150-005 |
Exametazine (Ceretec™) |
Ethyl Acetate 99.% |
150-130 |
Fluorodeoxyglucose (FDG)
|
Acetone (HPLC Grade) |
150-127 |
Glucoheptonate |
Acetone (HPLC Grade), Distilled H2O |
150-001 & 150-005 |
HDP |
Acetone (HPLC Grade), Distilled H2O |
150-001 & 150-005 |
MAA |
Acetone (HPLC Grade), |
150-001 |
MAG3 (Mertiatide™) |
Acetone, (HPLC Grade),
Chloroform 99.8%
Tetrahydrofuran 99+% |
150-951 & 150-952 |
MDP |
Acetone (HPLC Grade), Distilled H2O |
150-001 & 150-005 |
Mebrofenin (Cholotec™) |
150-160, Distilled H2O |
150-122 & 150-125 |
Pyrophosphate |
Acetone (HPLC Grade), Distilled H2O |
150-001 & 150-005 |
Sestamibi (Cardiolite™ and
Miraluma™) |
Ethyl Acetate 99.% |
150-991 |
Sulphur Colloid |
Acetone (HPLC Grade) |
150-001 |
Tc-99m (reduced) |
Acetone (HPLC Grade), |
150-001 |
Tc-99m Monoclonal Antibodies |
0.9% Saline |
150-771 |
Tetrofosmin (Myoview™) |
Ethyl Acetate 99.% |
150-971 |
In-111 Octreotide
(Octreoscan™) |
150-773 & 0.9% Saline |
150-771 ** |
In-111 Monoclonal
Antibodies |
150-773 & 0.9% Saline |
150-771 ** |
In-111/Y-90 Zevalin™ |
0.9% Saline |
150-772 |
I-131 Monoclonal Antibodies
And Neutrospec™ |
0.9% Saline |
150-771 |
* See Sigma-Aldrich product matrix for solvents.
** Note: A Well Plate is suggested to perform QC on these radiopharmaceuticals
Contact Fisher Scientific Corp. 800-766-7000 / www.fishersci.com / Item #14-245-71
RADIOPHARMACEUTICAL |
SOLVENT(S) REQUIRED* |
STRIPS REQUIRED |
Aluminum Breakthru |
150-781 10 µg/ml |
150-782 |
Aluminum Breakthru |
150-783 5 µg/ml |
150-782 |
Bicisate (Neurolite™) |
Ethyl Acetate 99.% |
150-130 |
Diphosphonate |
Acetone (HPLC Grade), Distilled H2O |
150-001 & 150-005 |
Disofenin (Hepatolite™) |
150-160, Distilled H2O |
150-122 & 150-125 |
DMSA |
Acetone (HPLC Grade), |
150-025 |
DTPA |
Acetone (HPLC Grade), Distilled H2O |
150-001 & 150-005 |
Exametazine (Ceretec™) |
Ethyl Acetate 99.% |
150-130 |
Fluorodeoxyglucose (FDG)
|
Acetone (HPLC Grade) |
150-127 |
Glucoheptonate |
Acetone (HPLC Grade), Distilled H2O |
150-001 & 150-005 |
HDP |
Acetone (HPLC Grade), Distilled H2O |
150-001 & 150-005 |
MAA |
Acetone (HPLC Grade), |
150-001 |
MAG3 (Mertiatide™) |
Acetone, (HPLC Grade),
Chloroform 99.8%
Tetrahydrofuran 99+% |
150-951 & 150-952 |
MDP |
Acetone (HPLC Grade), Distilled H2O |
150-001 & 150-005 |
Mebrofenin (Cholotec™) |
150-160, Distilled H2O |
150-122 & 150-125 |
Pyrophosphate |
Acetone (HPLC Grade), Distilled H2O |
150-001 & 150-005 |
Sestamibi (Cardiolite™ and
Miraluma™) |
Ethyl Acetate 99.% |
150-991 |
Sulphur Colloid |
Acetone (HPLC Grade) |
150-001 |
Tc-99m (reduced) |
Acetone (HPLC Grade), |
150-001 |
Tc-99m Monoclonal Antibodies |
0.9% Saline |
150-771 |
Tetrofosmin (Myoview™) |
Ethyl Acetate 99.% |
150-971 |
In-111 Octreotide
(Octreoscan™) |
150-773 & 0.9% Saline |
150-771 ** |
In-111 Monoclonal
Antibodies |
150-773 & 0.9% Saline |
150-771 ** |
In-111/Y-90 Zevalin™ |
0.9% Saline |
150-772 |
I-131 Monoclonal Antibodies
And Neutrospec™ |
0.9% Saline |
150-771 |
* See Sigma-Aldrich product matrix for solvents.
** Note: A Well Plate is suggested to perform QC on these radiopharmaceuticals
Contact Fisher Scientific Corp. 800-766-7000 / www.fishersci.com / Item #14-245-71
Manuals
-
Manual, Tec-Control Chromatography Strips, Red/Black, Operation
-
Manual, Tec-Control Chromatography Strips, Dark Green, Operation
-
Manual, Tec-Control Chromatography Strips, Blue, Operation
-
Manual, Tec-Control Chromatography Strips, Aluminum, Operation
-
Manual, Tec-Control Chromatography Strips, Red/Black, Operation
-
Manual, Tec-Control Chromatography Strips, Dark Green, Operation
-
Manual, Tec-Control Chromatography Strips, Blue, Operation
-
Manual, Tec-Control Chromatography Strips, Aluminum, Operation
Models and Ordering
To order, call +45 32 50 66 10
Chromatography Strips
150-001 |
Strips, RED, 50/pkg? |
150-005 |
Strips, BLACK, 50/pkg |
150-025 |
Strips, YELLOW, 50/pkg |
150-122 |
Strips, ORANGE, 50/pkg |
150-125 |
Strips, LIGHT BLUE, 50/pkg |
150-127 |
Strips, GREEN, 50/pkg |
150-130 |
Strips, GOLD, 50/pkg |
150-771 |
Strips, DARK GREEN, 50/pkg |
150-772 |
Strips, BLUE, 50/pkg |
150-951 |
Strips, LIME, 50/pkg |
150-952 |
Strips, PEACH, 50/pkg |
150-971 |
Strips, TEAL, 50/pkg |
150-991 |
Strips, PINK, 50/pkg |
150-782 |
Strips, ALUMINUM, 50/pkg |
Chromatography Solvents
150-160 |
Solvent, 20% Sodium Chloride, 30 ml? |
150-773 |
Solvent, DTPA, 5 ml |
150-781 |
Solvent, Aluminum Standard, 5 ml, 10 µg/ml |
150-783 |
Solvent, Aluminum Standard, 5 ml, 5 µg/ml |
Related Items:
150-960 |
Developing Vials, 10 ml, 288/case
(used for all Tec-Control testing)? |
150-961 |
Developing Vials, 5 ml, 144/case
(used for Sestamibi & Tetrofosmin) |
066-533 |
Forceps, Curved, Locking, 9.5" l
(24.1 cm) |
066-535 |
Forceps, Straight, Locking, 9.5" l
(24.1 cm) |
066-536 |
Forceps, Curved, Non-Locking,
12.5" l (31.7 cm) |
Tec-Control Solvent Vendor:
Sigma-Aldrich Chemical Company
800-558-9160 / www.sigmaaldrich.com
Note: Customers outside the US should visit Sigma-Aldrich web site to locate a regional office.
|
Solvent Description |
Vendor Part # |
Acetone HPLC Grade |
|
Ethyl Acetate 99.5% ACS Reagent |
|
Chloroform 99.8% ACS Reagent |
|
Tetrahydrofuran 99+% ACS Reagent |
|